Week 8 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay returns 25-1

Week 8 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay returns 25-1

Updated: 1 month, 2 days, 5 hours, 11 minutes, 49 seconds ago

The Tennessee Titans lost their first two games of the season, but they have responded with a four-game winning streak. Their most recent victory came in a crucial AFC South showdown against Indianapolis, as the Titans were able to sweep the season series. They have another divisional game on tap during the Week 8 NFL schedule. Tennessee is a 2-point road favorite at Houston in the latest Week 8 NFL odds at Caesars Sportsbook, while the over/under is 41. Should you back the Titans to extend their winning streak in the Week 8 NFL spreads? Which Week 8 NFL lines should you target with your Week 8 NFL bets? Before you make any Week 8 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 8 of the 2022 NFL season on an incredible 148-107 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 8. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 8 NFL picks at SportsLine.

Top Week 8 NFL picks

After simulating every game 10,000 times, the model is high on the Buffalo Bills (-10.5) to cover against the Green Bay Packers. Green Bay got off to a 3-1 start this season, but it has fallen off the tracks since then. The Packers are now on a three-game losing streak following a 23-21 loss at Washington, their longest skid since 2018. They had just 232 total yards of offense against the Commanders and lost wide receiver Allen Lazard to a shoulder injury. 

Buffalo is not an ideal opponent to face during a losing streak since the Bills have already blown three teams out this season. They raced past Pittsburgh in a 38-3 final three weeks ago and should be in line for another dominant win on Sunday. Buffalo is coming off its bye week, which is one of many reasons why SportsLine's model has the Bills covering the spread in well over 50% of simulations. See which other NFL parlay picks to make here.

How to make Week 8 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including backing an underdog that will win outright. You can only see the model's NFL Week 8 best bets and parlay at SportsLine. 

What are the model's top Week 8 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 8 NFL best bets from a model on a 148-107 run on its top-rated picks, and find out.